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27-Oct-2017 16:26

Most of the studies reviewed used doses that were twice the recommended amount -- 50 milligrams -- of diphenhydramine, the active ingredient in Benadryl and other first-generation "sedating" allergy medications.

"We're not saying that there's not a difference," says lead researcher Bruce G.

Bender, Ph D, of National Jewish Medical and Research Center in Denver.

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That study was sponsored by the company that manufactures Allegra.

The difference between them is really blurred." "Under some circumstances, the nonsedating formulas do cause sedation and in some cases, these sedating formulas do not," he tells Web MD.